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Abstract:
BACKGROUND:The current study aimed at examining whether individuals diagnosed with type 2 diabetes mellitus (T2DM) have more severe sleep disturbances compared to individuals who are healthy or have prediabetes and whether depressive symptoms mediate the relationship between sleep disturbances and having T2DM. METHODS:T2DM patients (n = 107) were compared to individuals with prediabetes (n = 48) and healthy individuals (n = 154) regarding the severity of depressive symptoms, measured via the Beck Depression Inventory-II (BDI-II), and sleep disturbances, measured via the Mini Sleep Questionnaire (MSQ). Mediation analysis examined whether depressive symptoms mediated the relationship between sleep disturbances and T2DM. RESULTS:Compared to healthy individuals and individuals with prediabetes, T2DM patients had more depressive symptoms and higher levels of insomnia, hypersomnia, and overall more sleep disturbances. The prediabetes group did not differ from the healthy control group on these measures, and these groups were thus combined for further analysis. Sleep disturbances were correlated with severity of depressive symptoms (r =0.43). After controlling for age, gender, and ethnic background, both severity of sleep disturbances (odds ratio [OR]: 1.04; 95% CI: 1.01-1.07, P <.001) and severity of depressive symptoms (OR: 8.54, 95% CI: 3.37-21.69, P <.001) predicted T2DM. Depression symptoms mediated the relationship between sleep disturbances and T2DM, whereas the direct relationship between sleep disturbances and T2DM was nonsignificant. CONCLUSIONS:The findings imply that sleep disturbances may contribute to the development and progression of T2DM by promoting depressive symptoms. Thus, treatments for the emotional distress associated with sleep disturbances may help reduce the risk for T2DM and the progression of the disease. :背景: 本研究旨在探讨2型糖尿病(T2DM)个体是否比健康人或糖尿病前期者有更严重的睡眠障碍, 以及抑郁症状在睡眠障碍与T2DM之间关系中的作用。 方法: 将107例T2DM患者与48例糖尿病前期患者及154例健康人进行比较, 采用Beck抑郁量表(BDI-II)测量抑郁症状的严重程度, 迷你睡眠问卷(MSQ)测量睡眠障碍。通过中介分析检验抑郁症状是否介导了睡眠障碍与T2DM之间的关系。 结果: 与健康人和糖尿病前期患者相比, T2DM患者有更多的抑郁症状, 更多的失眠, 多眠, 以及总体上更多的睡眠障碍。糖尿病前期组在这些指标上与健康对照组没有不同, 因此将这两组结合起来进行进一步分析。睡眠障碍与抑郁症状严重程度相关(r=0.43)。在控制了年龄、性别和民族背景后, 睡眠障碍的严重程度(OR:1.04;95%CI:1.01~1.07, P<0.001)和抑郁症状的严重程度(OR:8.54, 95%CI:3.37~21.69, P<0.001)均可预测T2DM。抑郁症状在睡眠障碍与T2DM的关系中起中介作用, 而睡眠障碍与T2DM的关系不显著。 结论: 睡眠障碍可能通过促进抑郁症状而参与T2DM的发生发展。因此, 对与睡眠障碍相关的情绪困扰的治疗可能有助于降低患T2DM的风险和疾病的进展。.
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最新影响因子:4.53 | 期刊ISSN:1753-0393 | CiteScore:2.13 |
出版周期: | 是否OA:YES | 出版年份:0 |
期刊官方网址:http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1753-0407
自引率:3.50% | 研究方向:ENDOCRINOLOGY & METABOLISM- |
出版地区:PEOPLES R CHINA |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Journal of Diabetes (JDB) devotes itself to diabetes research, therapeutics, and education. It aims to involve researchers and practitioners in a dialogue between East and West via all aspects of epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. The Editorial team is international with a unique mix of Asian and Western participation. The Journal has established a specific "Asia Track" to further this endeavor by bringing to the international community articles which focus on aspects of diabetes of particular relevance to Asia. The Editors welcome submissions in form of original research articles, images, novel case reports and correspondence, and will solicit reviews, point-counterpoint, commentaries, editorials, news highlights, and educational content.
《糖尿病杂志》致力于糖尿病研究、治疗和教育。它旨在通过流行病学、病因学、发病机制、管理、并发症和糖尿病预防的各个方面,包括糖尿病的分子、生化和生理方面,让研究人员和从业者参与东西方之间的对话。编辑团队是国际化的,有独特的亚洲和西方的参与。该杂志已经建立了一个特定的“亚洲追踪”,通过向国际社会提供与亚洲特别相关的糖尿病方面的文章来推进这一努力。编辑们欢迎以原创研究文章、图片、小说案例报告和信件的形式提交,并将征求评论、观点对位、评论、社论、新闻要点和教育内容。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
ENDOCRINOLOGY & METABOLISM (内分泌学与代谢) 3区 |
61/142 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
103 | 90 | 13 |
引文计数(2018)
文献(2015-2017)
690次引用
324篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Endocrinology, Diabetes and Metabolism
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研究方向:糖尿病
接受率: 中等(50%命中)
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研究方向:糖尿病 并发症
审稿时间: 3个月内 接受率: 一般容易(75%命中)
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研究方向:diabetes depression epidemiology
审稿时间: 6个月内 接受率: 一般容易(75%命中)
影响因子:2.655
ISSN:1520-9512
研究方向:医学-呼吸系统
影响因子:3.427
ISSN:1027-3719
研究方向:医学-传染病学
影响因子:4.09
ISSN:8755-6863
研究方向:医学-呼吸系统
影响因子:5.526
ISSN:1526-0542
研究方向:医学-呼吸系统
影响因子:2.973
ISSN:1472-9792
研究方向:医学-呼吸系统
影响因子:3.289
ISSN:2055-1010
研究方向:PRIMARY HEALTH CARE-RESPIRATORY SYSTEM
影响因子:10.262
ISSN:0012-3692
研究方向:医学-呼吸系统
影响因子:2.339
ISSN:0020-1324
研究方向:医学-呼吸系统
影响因子:102.642
ISSN:2213-2600
研究方向:RESPIRATORY SYSTEM-RESPIRATORY SYSTEM
发表一篇学和医学成像类SCI论文
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