发表一篇学和医学成像类SCI论文
需要多少钱?
Abstract:
CONTEXT:Clinically used endometrial (EM) receptivity assays are based on transcriptomic patterning of biopsies at midsecretory endometrium (MSE) to identify the possible displacement or disruption of window of implantation (WOI) in patients with recurrent implantation failure (RIF). However, biopsies are invasive and cannot be performed in the same cycle with in vitro fertilization embryo transfer, while uterine fluid (UF) analysis is considered minimally invasive and can immediately precede embryo transfer. OBJECTIVE:To determine whether UF proteome can be used for WOI monitoring and whether it would highlight the etiology of RIF. PATIENTS:Paired early secretory endometrial (ESE) and MSE UF samples from six fertile control women for discovery, and an additional 11 paired ESE/MSE samples from controls and 29 MSE samples from RIF patients for validation. RESULTS:Using discovery mass spectrometry (MS) proteomics we detected 3158 proteins from secretory phase UF of which 367 undergo significant (q < 0.05) proteomic changes while transitioning from ESE to MSE. Forty-five proteins were further validated with targeted MS, and 21 were found to display similar levels between control ESE and RIF MSE, indicating displacement of the WOI. A panel of PGR, NNMT, SLC26A2 and LCN2 demonstrated specificity and sensitivity of 91.7% for distinguishing MSE from ESE samples. The same panel distinguished control MSE samples from RIF MSE with a 91.7% specificity and 96.6% sensitivity. CONCLUSION:UF proteins can be used for estimating uterine receptivity with minimal invasiveness. Women with RIF appear to have altered MSE UF profiles that may contribute to their low IVF success rate.
展开更多
最新影响因子:6.134 | 期刊ISSN:0021-972X | CiteScore:0.0 |
出版周期:Monthly | 是否OA:YES | 出版年份:1952 |
自引率:4.00% | 研究方向:医学-内分泌学与代谢 |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
专业编辑在线一对一答疑及时解决您的问题
The Journal of Clinical Endocrinology & Metabolism is the world''s leading peer reviewed journal of clinical practice and applied clinical research. Each issue provides fast and in depth coverage of diabetes, reproductive endocrinology, growth hormone therapy, thyroid disease, and other critical areas of clinical endocrinology. Regular features highlight current topics in clinical medicine, such as clinical studies, clinical case seminars, management of endocrine disorders, practice management issues, original patent oriented research studies, and other significant new endocrine studies related to human physiology and disease. According to the latest ISI Journal Citation Report, JCE&M articles were cited almost 38,000 times in 2000. It has the highest Impact Factor ranking (#9) of any clinical journal in the ISI category of endocrinology and metabolism.
《临床内分泌与代谢杂志》是世界领先的临床实践和应用临床研究的同行评审期刊。每个问题提供快速和深入的报道糖尿病,生殖内分泌学,生长激素治疗,甲状腺疾病和其他关键领域的临床内分泌。定期专题突出当前临床医学的主题,如临床研究、临床病例研讨会、内分泌疾病管理、实践管理问题、原始专利导向的研究,以及其他与人类生理和疾病相关的重要内分泌新研究。根据ISI期刊最新的引文报告,2000年,JCE&M的文章被引用了近3.8万次。在内分泌和代谢的ISI分类中,它是所有临床杂志中影响因子排名最高的(第9)。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
ENDOCRINOLOGY & METABOLISM (内分泌学与代谢) 2区 |
20/142 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
491 | 476 | 15 |
引文计数(2018)
文献(2015-2017)
0次引用
99篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Endocrinology, Diabetes and Metabolism
|
#208/209
点击查看排名表
|
|
推荐刊物均可到国家新闻出
版总署网站查询正刊
可签署保密协议 ,不透露任
何用户信息可跟踪进程,全程
协议
1对1服务,7x24小时在线
16年经验沉淀,实体公司
运营
liting7111
研究方向:代谢
liting7111
研究方向:代谢
liting7111
研究方向:甲状腺癌 临床 治疗
审稿时间: 2个月内 接受率: 比较困难(25%命中)
liting7111
研究方向:代谢
liting7111
研究方向:糖尿病手术
接受率: 比较困难(25%命中)
liting7111
研究方向:代谢
liting7111
研究方向:代谢
liting7111
研究方向:代谢
liting7111
liting7111
liting7111
研究方向:代谢
liting7111
liting7111
研究方向:代谢
liting7111
研究方向:内分泌
liting7111
研究方向:代谢
审稿时间: 1个月内
liting7111
研究方向:diabetes thrombosis
liting7111
研究方向:代谢
liting7111
研究方向:代谢
liting7111
liting7111
研究方向:代谢
liting7111
研究方向:糖尿病
接受率: 比较困难(25%命中)
liting7111
研究方向:甲状旁腺功能减退症 基因多态性 治疗
liting7111
研究方向:代谢
接受率: 比较困难(25%命中)
liting7111
liting7111
研究方向:代谢
liting7111
研究方向:代谢
影响因子:1.714
ISSN:1386-2073
研究方向:化学-生化研究方法
影响因子:6.088
ISSN:1933-7213
研究方向:医学-神经科学
影响因子:1.379
ISSN:0362-5664
研究方向:医学-临床神经学
影响因子:4.287
ISSN:1473-7175
研究方向:CLINICAL NEUROLOGY-PHARMACOLOGY & PHARMACY
影响因子:1.821
ISSN:1528-4336
研究方向:医学-传染病学
影响因子:2.385
ISSN:1120-009X
研究方向:医学-药学
影响因子:2.706
ISSN:1076-6294
研究方向:医学-传染病学
影响因子:4.177
ISSN:1178-6973
研究方向:-
影响因子:5.758
ISSN:0305-7453
研究方向:医学-传染病学
发表一篇学和医学成像类SCI论文
需要多少钱?
专注医学期刊服务16年
您好:请问您咨询什么等级的期刊?专注医学类期刊发表16年口碑企业,为您提供以下服务:
1.医学核心期刊发表-全流程服务
2.医学SCI期刊-全流程服务
3.论文投稿服务-快速报价
4.期刊推荐直至录用,不成功不收费
客服正在输入...
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 投稿经验
(由下方点评分析获得,26人参与,89769人阅读)