发表一篇学和医学成像类SCI论文
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Abstract:
INTRODUCTION:So far, anti-PD-1/anti-PD-L1 antibody therapy is reportedly in treating gastric cancer or gastro-oesophageal junction cancer (GC/GEJC) in a number of clinical trials. Based on this, we conducted current meta-analysis to assess the safety and efficacy of anti-PD-1/anti-PD-L1 antibody for previously treated advanced GC/GEJC patients. METHODS:We searched five electronic databases for eligible records. Outcomes were presented and analyzed by objective response rate (ORR), disease control rate (DCR), progression-free survival (PFS), overall survival (OS) and adverse effects (AEs). RESULTS:Nine records involving 1388 participants were selected in our study. The pooled ORR, DCR, OS rate (6 month), PFS rate (6 month), OS rate (12 month) and PFS rate (12 month) were 10% (95% confidence interval [CI]: 6%-14%), 32% (95%CI: 25%-38%), 52% (95%CI: 44%-61%), 18% (95%CI: 13%-24%), 40% (95%CI: 31%-48%) and 8% (95%CI: 5%-10%), respectively. Meanwhile, grade≥3 AEs rate was 12% (95% CI: 10%-15%). Programmed death ligand 1 (PD-L1) positive cases had higher rate of ORR (odds ratio [OR]: 3.75, 95%CI: 2.09-6.74, P=0.58) compared with negative cases. CONCLUSION:The results indicated that anti-PD-1/anti-PD-L1 antibody therapy has an effectual anti-tumor activity and controllable AEs in advanced GC/GEJC patients. Furthermore, overexpression of PD-L1 in advanced GC/GEJC patients had better ORR from anti-PD-1/anti-PD-L1 antibody therapy (PROSPERO registration number: CRD42018116480).
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最新影响因子:3.189 | 期刊ISSN:2210-7401 | CiteScore:1.86 |
出版周期: | 是否OA:YES | 出版年份:2011 |
期刊官方网址:http://www.journals.elsevier.com/clinics-and-research-in-hepatology-and-gastroenterology/
期刊投稿地址:http://ees.elsevier.com/gcb/
自引率:1.40% | 研究方向:GASTROENTEROLOGY & HEPATOLOGY- |
出版地区:FRANCE |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Clinics and Research in Hepatology and Gastroenterology has an open access mirror journal Clinics and Research in Hepatology and Gastroenterology: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. Clinics and Research in Hepatology and Gastroenterology publishes high quality papers in the field of hepatology and gastroenterology in English language. The editors put the accent on rapid communication of new research and clinical developments and so called "hot topic" issues. Following a clear Editorial line, besides original articles and case reports, each issue features editorials, commentaries, a seminar, mini-reviews, pictorial reviews and several keynotes. The journal encourages research and discussion between all those involved in the specialty on an international level. Articles in press are online and indexed in the international databases (Current Contents, Pubmed, Scopus, Science Direct).
在肝病学和胃肠病学方面的诊所和研究有一个开放的镜象。杂志在肝病学和胃肠病学方面的诊所和研究:X,目标和范围相同,编辑团队,提交系统和严格的同行评审。 在肝病学和胃肠病学方面的诊所和研究发表了高质量的英语肝病学和胃肠病学领域的论文。编辑把重点放在新的研究和临床发展的快速交流上,称之为“热点”问题。除了原创文章和案例报告外,每一期都有明确的编辑路线,包括社论、评论、研讨会、小型评论、图片评论和若干要点。该期刊鼓励所有在国际层面从事这一专业的人进行研究和讨论。报刊上的文章都是在线的,并在国际数据库中进行索引(当前的内容、公开、范围、科学直接)。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
GASTROENTEROLOGY & HEPATOLOGY (胃肠肝病学) 4区 |
56/80 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
84 | 66 | 18 |
引文计数(2018)
文献(2015-2017)
800次引用
431篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Hepatology
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#35/59
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2 |
大类(学科):Medicine
小类(学科):Gastroenterology
|
#58/128
点击查看排名表
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liting7111
研究方向:消化病 胃肠道
liting7111
研究方向:腹腔镜
liting7111
研究方向:消化病 胃肠道
审稿时间: 3个月内
liting7111
研究方向:消化病 胃肠道
审稿时间: 2个月内 接受率: 一般容易(75%命中)
liting7111
研究方向:消化病 胃肠道
审稿时间: 3个月内 接受率: 一般容易(75%命中)
liting7111
审稿时间: 3个月内 接受率: 中等(50%命中)
liting7111
接受率: 比较困难(25%命中)
影响因子:2.995
ISSN:0028-3940
研究方向:医学-核医学
影响因子:2.324
ISSN:1051-2284
研究方向:医学-核医学
影响因子:3.156
ISSN:1869-1439
研究方向:CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & M
影响因子:4.6
ISSN:0150-9861
研究方向:医学-核医学
影响因子:1.764
ISSN:1591-0199
研究方向:CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & M
影响因子:4.966
ISSN:0195-6108
研究方向:医学-核医学
影响因子:3.005
ISSN:0301-0449
研究方向:医学-核医学
影响因子:2.396
ISSN:1793-5458
研究方向:OPTICS-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGI
影响因子:3.632
ISSN:1084-9785
研究方向:医学-核医学
发表一篇学和医学成像类SCI论文
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