发表一篇学和医学成像类SCI论文
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Abstract:
:Thymic epithelial tumors (TETs) are uncommon neoplasms of the mediastinum. The gold standard treatment is complete surgical resection which can be followed by radio/chemotherapy in selected cases. Targeted tyrosine kinase inhibition can be considered in only a limited number of aggressive or metastatic tumors as EGFR, BRAF, or c-kit mutations are rare. However, previous studies have demonstrated the efficacy of immune checkpoint inhibitors in epithelial neoplasias, such as in programmed cell death ligand 1 (PD-L1) expressing nonsmall cell lung carcinoma. Because of their rare occurrence the data on PD-L1 distribution in thymic neoplasias are limited. PD-L1 and PD-1 expression in tumor cells and tumor infiltrating immune cells was determined in TETs according to criteria published for lung carcinomas. Comparison with major clinical, pathologic, and biological features was also done. In total, 36 TETs (29 thymomas and 7 thymic carcinomas) were analyzed. PD-L1 immunohistochemical staining (Ventana PD-L1 clone SP142) was performed in all cases. The percentage of the positive tumor cells (TC value), the percentage of tumor area occupied by positive immune cells (IC value) was evaluated. Evaluation of PD-L1 expression in tumor cells showed a good reproducibility (κ-value: 0.840; Spearman r=0.966; P
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最新影响因子:1.992 | 期刊ISSN:1541-2016 | CiteScore:N/A |
出版周期: | 是否OA:YES | 出版年份:0 |
期刊官方网址:http://journals.lww.com/appliedimmunohist/pages/default.aspx
自引率:6.90% | 研究方向:ANATOMY & MORPHOLOGY-MEDICAL LABORATORY TECHNOLOGY |
出版地区:UNITED STATES |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Applied Immunohistochemistry & Molecular Morphology covers newly developed identification and detection technologies, and their applications in research and diagnosis for the applied immunohistochemist & molecular Morphologist. Official Journal of the International Society for Immunohistochemisty and Molecular Morphology.
应用免疫组织化学和分子形态学包括最新开发的识别和检测技术,以及它们在应用免疫组织化学和分子形态学学家的研究和诊断中的应用。 国际免疫组织化学和分子形态学学会官方刊物。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
ANATOMY & MORPHOLOGY (解剖学与形态学) 3区 MEDICAL LABORATORY TECHNOLOGY (医学实验技术) 3区 PATHOLOGY (病理学) 3区 |
6/21 15/30 36/79 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
122 | 114 | 8 |
引文计数(2018)
文献(2015-2017)
N/A次引用
N/A篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Medicine
小类(学科):Anatomy
|
#0/35
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|
2 |
大类(学科):Health Professions
小类(学科):Medical Laboratory Technology
|
#0/28
点击查看排名表
|
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研究方向:医学 解剖学 形态学
审稿时间: 3个月内
影响因子:1.714
ISSN:1386-2073
研究方向:化学-生化研究方法
影响因子:6.088
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研究方向:医学-神经科学
影响因子:1.379
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影响因子:4.287
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研究方向:CLINICAL NEUROLOGY-PHARMACOLOGY & PHARMACY
影响因子:1.821
ISSN:1528-4336
研究方向:医学-传染病学
影响因子:2.385
ISSN:1120-009X
研究方向:医学-药学
影响因子:2.706
ISSN:1076-6294
研究方向:医学-传染病学
影响因子:4.177
ISSN:1178-6973
研究方向:-
影响因子:5.758
ISSN:0305-7453
研究方向:医学-传染病学
发表一篇学和医学成像类SCI论文
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