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Prognostic factors for unfavourable outcomes of patients with spinal tuberculosis in a country with an intermediate tuberculosis burden: a multicentre cohort study.
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Abstract:
AIMS:Spinal tuberculosis (TB) remains an important concern. Although spinal TB often has sequelae such as myelopathy after treatment, the predictive factors affecting such unfavourable outcomes are not yet established. We investigated the clinical manifestations and predictors of unfavourable treatment outcomes in patients with spinal TB. PATIENTS AND METHODS:We performed a multicentre retrospective cohort study of patients with spinal TB. Unfavourable outcome was defined according to previous studies. The prognostic factors for unfavourable outcomes as the primary outcome were determined using multivariable logistic regression analysis and a linear mixed model was used to compare time course of inflammatory markers during treatment. A total of 185 patients were included, of whom 59 patients had unfavourable outcomes. RESULTS:In multivariate regression analysis, the factors associated with unfavourable outcome were old age (odds ratio (OR) 2.51; 95% confidence interval (CI) 1.07 to 5.86; p = 0.034), acid-fast bacilli (AFB) smear positivity in specimens obtained through biopsy (OR 3.05; 95% CI 1.06 to 8.80; p = 0.039), and elevated erythrocyte sedimentation rate (ESR) at the end of treatment (OR 3.85; 95% CI 1.62 to 9.13; p = 0.002). Patients with unfavourable outcomes had a significant trend toward higher ESR during treatment compared with patients with favourable outcome (p = 0.009). Duration of anti-TB and surgical treatment did not affect prognosis. CONCLUSION:Elevated ESR at the end of treatment could be used as a marker to identify spinal TB patients with a poor prognosis. Patients whose ESR is not normalized during treatment, as well as those with old age and AFB smear positivity, should be aware of unfavourable outcomes. Cite this article: Bone Joint J 2019;101-B:1542-1549.
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Bone & Joint Journal
BONE JOINT J
| 最新影响因子：5.385 | 期刊ISSN：2049-4394 | CiteScore：N/A |
| 出版周期： | 是否OA：YES | 出版年份：0 |
| 自引率：22.80% | 研究方向：ORTHOPEDICS-SURGERY |
| 出版地区：ENGLAND |
SCI期刊coverage：Science Citation Index Expanded（科学引文索引扩展）
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Bone & Joint Journal 期刊简介
英文简介：
The Journal of Bone & Joint Surgery [Br] was first published in February 1948 and shared the title The Journal of Bone & Joint Surgery with the American Volume of JBJS. The two volumes were editorially and financially independent. If you are interested in a detailed history of The Journal of Bone & Joint Surgery [Br] and the many great names associated with the journal, listen to our podcast on the subject by Frank Horan. In September 2011, JBJS (Am) and JBJS (Br) reached a joint agreement on future, independent operations. This new agreement now gives each Journal more autonomy over its future direction and strategy. Relaunched as The Bone & Joint Journal in 2012, the journal publishes monthly issues. To find information on the current BJJ Editorial Board click here, or alternatively information on the Society's Council of Management. Orthopaedic Proceedings is a supplement with BJJ that publishes abstracts from major orthopaedic meetings around the world online. The new and improved Orthopaedic Proceedings archive can be found here. The abstracts from the European Federation of National Associations of Orthopaedics and Traumatology Annual Congress are published in print in addition to online. The Bone & Joint Journal is the official publication of many national and international Associations.
中文简介：（来自Google、百度翻译）
《骨与关节外科杂志》于1948年2月首次出版，并与美国JBJS合著了《骨与关节外科杂志》（Journal of Bone&Joint Survey）。这两卷书在编辑上和经济上都是独立的。如果你对《骨关节外科杂志》的详细历史以及与该杂志相关的许多伟大的名字感兴趣，请关注我们关于弗兰克·霍兰主题的播客。 2011年9月，JBJS（AM）和JBJS（BR）就未来独立运营达成了联合协议。这项新的协议现在给了每一家杂志更多的未来方向和战略的自主权。该杂志于2012年作为骨关节杂志重新发行，每月发行一期。要在当前的BJJ编委会上找到信息，请单击此处，或者是社会管理委员会的信息。 《骨科会议录》是BJJ的一个补充，它在世界各地的大型骨科会议上在线发表摘要。新的和改进的骨科程序档案可以在这里找到。欧洲骨科和创伤学全国协会联合会年度大会的摘要除了在线发布外，还以印刷形式发布。 骨关节杂志是许多国家和国际协会的官方出版物。
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Bone & Joint Journal 期刊中科院评价数据
最新中科院分区
| 大类(学科) | 小类(学科) | 学科排名 |
| 医学 |
ORTHOPEDICS (骨科) 2区 SURGERY (外科) 2区 |
7/77 27/200 |
最新公布的期刊年发文量
| 年度总发文量 | 年度论文发表量 | 年度综述发表量 |
| 246 | 230 | 16 |
总被引频次：5865
特征因子：0.024380
影响因子趋势图
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Bone & Joint Journal 期刊CiteScore评价数据
最新CiteScore值
N/A
=
引文计数(2018)
文献(2015-2017)
=
N/A次引用
N/A篇文献
文献总数（2014-2016）：N/A
被引比率：N/A%
SJR：0.202
SCLmago期刊等级衡量经过加权后的期刊受引用次数，引用次数的加权值由施引期刊的学科领域和声望(SJR)决定。
SNIP：0.153
每篇文章中来源出版物的标准化影响将实际受引用情况对照期刊所属学科领域中预期的受引用情况进行衡量。
CiteScore排名
| 序号 | 类别 | 排名 | 百分位 |
| 1 |
大类(学科)：Medicine
小类(学科)：Endocrinology, Diabetes and Metabolism
|
#0/209
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|
| 2 |
大类(学科)：Medicine
小类(学科)：Orthopedics and Sports Medicine
|
#0/237
点击查看排名表
|
|
CiteScore趋势图
Scopus涵盖范围
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