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Abstract:
:Prolonged duration of obstructive apnea (OA) has been observed in highlanders after descending to low altitude. It is proposed that due to adaptation to a hypoxic high-altitude environment, Tibetan highlanders (TH) and Han highlanders (HH) would manifest different OA durations at low altitude as compared to Han lowlanders (HL). Data collection on consecutive obstructive sleep apnea patients (167 TH, 210 HH and 233 HL) was performed over a period of 8 years in Chengdu (altitude 500 m). The analyses were performed with non-matched groups and with body mass index and apnea-hypopnea index-matched groups. Significance rankings for mean duration of OA (s) in non-matched groups and matched groups were TH (27.7; 28.6) = HH (25.7; 26.0) > HL (21.7; 21.3), respectively. For the longest OA duration, the significance rankings across three groups with regard to the percentage of patients having a duration longer than 2 min (%) and mean values (s) were TH (26.9; 82) > HH (10.0; 67) > HL (1.3; 50). In terms of nadir and mean oxygen saturation, significant differences were found between TH and HH or HL. In addition, longest and mean OA duration were positively correlated with blood pressure and heart rate, whereas nadir and mean oxygen saturation were negatively correlated with these measures in both non-matched and matched groups, and the correlation was more robust in TH. These findings raise important clinical questions regarding whether such significant prolongation of OA duration and a more severe hypoxic burden among highlanders, especially in TH, may lead to adverse clinical consequences when at low altitude.
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最新影响因子:5.296 | 期刊ISSN:0962-1105 | CiteScore:3.36 |
出版周期:Quarterly | 是否OA:YES | 出版年份:1992 |
期刊官方网址:http://onlinelibrary.wiley.com/journal/10.1111/%28ISSN%291365-2869
自引率:3.90% | 研究方向:医学-临床神经学 |
出版地区:ENGLAND |
SCI期刊coverage:Science Citation Index Expanded(科学引文索引扩展)
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Official Journal of the European Sleep Research Society. The Journal of Sleep Research is an international journal that encourages important research papers presenting new findings in the field of sleep and wakefulness (including biological rhythms and dreaming). The Journal reflects the progress in this rapidly expanding field, promoting the exchange of ideas between scientists at a global level.
欧洲睡眠研究学会官方期刊。《睡眠研究杂志》(Journal of Sleep Research)是一份国际期刊,鼓励发表有关睡眠和觉醒(包括生物节律和做梦)领域新发现的重要研究论文。该杂志反映了这一迅速扩大的领域的进展,促进了全球科学家之间的思想交流。
大类(学科) | 小类(学科) | 学科排名 |
医学 |
CLINICAL NEUROLOGY (临床神经病学) 3区 NEUROSCIENCES (神经科学) 3区 |
60/197 100/261 |
年度总发文量 | 年度论文发表量 | 年度综述发表量 |
100 | 97 | 3 |
引文计数(2018)
文献(2015-2017)
958次引用
285篇文献
序号 | 类别 | 排名 | 百分位 |
1 |
大类(学科):Neuroscience
小类(学科):Cognitive Neuroscience
|
#24/90
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2 |
大类(学科):Neuroscience
小类(学科):Behavioral Neuroscience
|
#8/68
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发表一篇学和医学成像类SCI论文
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