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Absract: There has been proved the link between the intestinal microbiota composition characteristics and the development of diseases,in particular colorectal cancer,kidney failure,irritable bowel syndrome,intestinal infec-tions,obesity,type I diabetes and metabolic syndrome (MS).Metagenomic studies demonstrated the presence of significant differences in the structure of the intestinal microbiota in populations of Europeans and Asians.In this as-pect,the Xinjiang Uygur Autonomous region of China is the most affected district,where substantially the indige-nous Uighur,Kazakh and also Han populations is affected.There is an objective need to ascertain the microecologi-cal and metabolic status of persons of the indigenous population in Western China,which are in the risk zone.The test for microalbuminuria is reliable method of kidney failure primary stages diagnosis,reflecting the initial stages of vessel pathology and the development of MS.It invariably correlates with an increase of cardiovascular morbidity and mortality.We introduce this screening test for early detection of predisposition to the development of the MS in the example of Xinjiang population for use also in other regions of China.There is a need to carry out the search,selec-tion and analysis of the new strains of probiotics in the Xinjiang from national milk products with lactic acid or other fermented products with the purpose of studying their clinical characteristics.This will have an impact on increasing life expectancy and improving the quality of life of the population of Xinj iang.