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Objective:To observe the effects of Banxiaxiexin Decoction (BD) on rats with electrogastric dysrhythmias by divided design and discuss the mechanism of BD. Methods:To establish the rat model of electrogastric dysrhythmias and examine effects of BD on the SCF mRNA by reverse transcriptive polymerase chain reaction (RT-PCR).Results:BD and all the divided groups can reduce the mRNA expression of SCF, and show significant difference with model group (P0.05).Conclusion:The BD treatment of epigastric fullness (to regulate the movement of stomach and intestine) is in connection with adjustment of the mRNA expression of SCF.