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痴呆与白质疏松诊断的相关性分析
Background: Clinical doctors and radiographers have found the phenomenon that the density of white matter decrease particularly in some patients,and Hachinski called it as Leuko araeosis(LA).LA is a imageological diagnosis,and there were a lot of contentions about the LA substances and the clinical significance of LA.Some considered the neural pathological basis was demyelination of white matter and proliferation of glyocytes.Other persons suggested that the lower density focuses were combined appearances of incomplete ischemia micro infarction and demyelination of white matter .Recently some have observed the phenomenon was similar to Binswanger's disease(BD) in autopsy, but it has been contentious whether BD is same disease entity as the LA and the relationship between LA and brain infarction. So we analyzed the clinical and imaging data of 84 patients with LA revealed by CT and MRI, and discussed the diagnosis of LA with the help of recent international and national literatures. Objective: To explore the relativity of diagnosis between dementia and leuko araeosis.
