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Objective: To observe the effect of acupoint massage in relieving pain after ureteroscopic holmium laser lithotripsy.
Methods: Ninety-two patients undergone ureteroscopic holmium laser lithotripsy were enrolled and randomized into a treatment group and a control group, 46 in each group. Patients in the control group were given regular nursing care, while patients in the treatment group were intervened by acupoint massage in addition to the regular nursing care. The pain was evaluated by visual analogue scale (VAS) at 6 h, 12 h, and 24 h after operation, and compared between the two groups.
Results:There was no significant difference in comparing the VAS score at 6 h after operation between the two groups (P>0.05). The VAS scores in the treatment group at 12 h and 24 h after operation were significantly lower than those in the control group (both P<0.05). Fewer patients in the treatment group used analgesics compared with those in the control group.
Conclusion: Acupoint massage can effectively relieve the pain after ureteroscopic holmium laser lithotripsy, reduce the use of analgesics, and promote the recovery. -
心肌缺血犬经激光心肌血管重建后VEGF和bFGF的变化及心肌血管新生
目的:观察激光心肌血管重建术(TMLR)后血管内皮细胞生长因子(VEGF)和碱性成纤维细胞生长因子(bFGF)与新生血管密度的关系.方法:北京地区杂种犬25只,以单纯缺血为对照组5只(3 d、1、2、4周和8周)5个时相检测血浆中VEGF、bFGF水平;实验组行心肌打孔后(1、2、4、8周)4个时相,每时相均为5只活杀显微镜下观察心肌血管密度的变化.结果:实验组VEGF和bFGF血浆浓度分别在术后2周和1周达高峰[(1.84±0.85)ng/L和(2.54±0.48n/L)],心肌血管密度在术后4周达高峰(10.23‰±2.23‰).结论:TMLR术可通过介导致血管生成的生长因子(如VEGF和bFGF)的表达来达到其部分血管新生的作用.