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Objective:To investigate the potential role of KAI1 in epithelial ovarian carcinoma(EOC), and to determine whether the expression of the KAI1 gene is associated with EOC progression.The clinical significance in this tumor is also evaluated.Method: Immunohistochemistry SP method was performed to examine the expression level of KAI1 in EOC.Results: Thirty eight of 66 cancer specimens showed KAI1 protein positive (57.58%),which lower significantly than that in the patients with benign and borderline tumors(90.91%).The statistical evaluation showed that the expression of KAI1 had a correlation with FIGO stags as well as lymph node metastasis(or distant metastasis)(P<0.05).It also revealed an inverse relationship between histological grade and KAI1 expression (P<0.05).Conclusion: KAI1 protein expression is closely correlated with the malignent progression and metastasis of EOC; detecting the expression of KAI1 probably possesses clinical significance in evaluating the differentiation,tumor progression and predicting the prognosis of EOC.
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异位妊娠与卵巢肿瘤的鉴别诊断
症状不典型的异位妊娠,特别是陈旧性异位妊娠的临床诊断较困难,影像检查中极易与卵巢肿瘤及炎性包块混淆.为提高对它们的鉴别诊断,我们对18例异位妊娠,46例卵巢肿瘤的CT表现作一回顾性分析,试图揭示其CT表现特点.
