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RAGE in Cancer Lung:the End of a Long and Winding Road is in Sight
IntroductionThe receptor of advanced glycation end-products (RAGE), is a type Ⅰ single-pass transmembrane protein, member of the multi-ligand immunoglobulin superfamily molecule, which was discovered in 1992, on account of its ability to bind the advanced glycation end-products (AGEs)[1].