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BACKGROUND:?Ectopic?pancreatic?tissue?is?relatively?uncommon,?and?is?characterized?as?pancreatic?tissue?with?no?contact?with?the?normal?pancreas,?and?with?its?own?ductal?system?and?blood?supply.?It?is?usually?asymptomatic,?and?can?be?incidentally?diagnosed?by?conventional?imaging?studies. METHOD:?A? 69-year-old? woman? with? a? prior? history? of?bilateral?breast?carcinoma?presented?with?ectopic?pancreatic?intraepithelial?neoplasia?(PanIN)?that?was?identiifed?incidentally?in? the? small? bowel? during? an? oncological? resection? of? a?synchronous?primary?pancreatic?adenocarcinoma,?and?renal?cell?carcinoma. RESULTS:?The?patient?underwent?subtotal?pancreatectomy?with?splenectomy,?regional?lymphadenectomy,?radical?left?nephrectomy,?and?small?bowel?resection?with?primary?anastomosis?of?ectopic?PanIN-2.? She? had? an? uneventful? hospitalization? and? was?discharged?home?on?postoperative?day?7. CONCLUSIONS:?The?occurrence?of?ectopic?PanIN?is?extremely?unusual?with?only?few?cases?previously?reported?in?the?literature.?The?need?for?negative?margins?after?surgical?resection?of?ectopic?PanIN?lesions?remains?controversial.