慢性阻塞性肺病患者血浆一氧化氮、内皮素和降钙素基因相关肽的含量变化

慢性阻塞性肺病(COPD)是一种重要而常见的慢性呼吸系统疾病,患病人数多,死亡率高,而且随着COPD病情进展,逐渐合并肺原性心脏病,呼吸衰竭,严重影响了患者的身体健康和生活质量.近年来,人们逐渐认识到血管内皮合成释放的某些重要血管活性物质如ET-1、CGRP与COPD密切相关,参与了COPD、肺心病、呼吸衰竭的病理生理过程.本研究观测了COPD各病情组患者的血浆NO、ET-1和CGRP的含量变化.

输入同型血浆诱发哮喘及过敏性休克1例的抢救与护理

临床中输人血液制品是常见的治疗措施.在输注过程中可发生各种不良反应,常见的输血反应有发热反应、过敏反应、溶血反应[1].过敏反应以皮肤瘙痒、荨麻疹较为多见,但发生过敏性休克者很少出现.通过回顾1例输入同型血浆发生哮喘及过敏性休克病人的抢救,探讨发生原因、护理措施和对症处理.提示,医务人员在临床工作中应给予足够重视,保证病人的输血安全.

AIM: Umbilical cord blood plasma contain higher hematopoietic stimulatory activities than adult peripheral blood plasma. IL-3 is regarded as multilineage hematopoietic growth factor that acts on primitive pluripotential stem cells and progenitor cells of every lineage except T and B-lymphoid lineage.

Objective:　To evaluate the effect and safety of early moderate hypothermia therapy (MHT) on patients with head injury by using parallel-control test.　　Methods:　Thirty patients with severe head injury within 6 hours after accidents were treated by MHT generally for 4-10 days. The other 30 patients with similar head injury treated routinely were enrolled for a parallel-control test. The mortality, morbidity and changes of some neuro-functional indexes as Glasgow Coma Scores, and Glasgow Outcome Scale, levels of endothelin and some other factors of neurobiochemistry in blood plasma were observed. Meanwhile, the dynamic monitoring by transcranial Doppler ultrasonography was conducted in these patients.　　Results:　The mortality in MHT group was significantly lower than that in control group. MHT not only reduced endothelin but also increased the brain biochemical factors, which were helpful to the protection of neurons in the early brain ischemia after head injury.　　Conclusions:　Early MHT can help reduce mortality and morbidity in patients with acute head injury.