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ATC/DDD系统的建立及其在药物利用研究中的应用
药物利用研究(studies of drug utilization)始于20世纪60年代初,初仅局限于对药物上市后消耗量的研究,随着上市新药的不断涌现和药品消耗结构的变化,药物消费呈现迅速增长趋势,对药物消耗量、消费结构、处方习惯和不良反应等方面的研究也有了较大的进展[1].
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2003～2005年我院口服降糖药物利用分析
To assess the drug utilization and tendency of progress of oral hypoglycemic agents in our hospital and to provide references for rational administration clinically. Methods: DDDs, sales quantities, sales expenses and the ratio of sales expenses sequencing to that of DDDs in our hospital during the period of 2003 ～ 2005 were analyzed statistically with the method of DDDs analysis. Results:The top two antidiabetic drugs according to DDDs were melbine ( dimethyl diguanide) and gliclazide three successive years. The DDDs of acarbose increased dramatically. Which blood glucose regulatsry drugs ranked lower, the ratio of sales expenses sequencing to that of DDDs of glipizide and gliclazide controlled release pellets was equal or about, whereas that of rosiglitazone, acarbose(glucobay) and glimepiride was less than 1. Conclusion:The study shows that the drug utilization of oral hypoglycemic agents in our hospital is basically rational and is in accordance with the trend of advancement and drug therapeutic strategies of diabetes mellitus.
