首页 > 文献资料
-
健康教育在预防小学生龋齿及近视中的作用初探
对小学生进行健康教育,使他们从小养成良好的卫生习惯,是预防龋齿和近视的一个重要措施.为考察健康教育在预防龋齿及近视中的作用,湖北省孝感市卫生防疫站、孝感市中心医院眼科于1999年对本地区已开设健康教育课的农村小学和未开设健康教育课的农村小学进行了调查,现将结果报告如下.
-
口腔健康促进与我国氟化物防龋的开展
20世纪90年代我国口腔卫生保健工作走上了一条有组织、有目标、有规划的发展道路,在卫生部的领导下,通过专家的努力,为实现人人享有口腔卫生保健的目标开展了一系列的活动,取得了显著的成绩.其中,在推广有效应用氟化物预防龋齿方面组织开展了大量的研究和促进活动,有效提高了广大群众,特别是儿童青少年的口腔健康水平.
-
窝沟封闭剂防龋的临床效果观察
后牙牙合面窝沟是龋病的好发区,尤其是第一恒磨牙为常见.有学者统计恒牙的窝沟龋占龋病的84.7%[1],窝沟封闭能有效地预防龋病.应城市人民医院口腔科于2005年5月,从6~9岁的适龄儿童中选择无龋病的第一恒磨牙(4颗)儿童行窝沟封闭术,共计200例,经3年临床观察分析,效果较好,现报告如下.1 资料与方法1.1一般资料200例儿童年龄6~9岁,在性别上无差异,儿童第一恒磨牙(4颗)共计800颗, 完全萌出、无龋病,牙牙合面窝沟较深,行窝沟封闭术.
-
Streptococcus mutans is a common Gram-positive bacterium and plays a significant role in dental caries. Tobacco and/or nicotine have documented effects on S. mutans growth and colonization. Sortase A is used by many Gram-positive bacteria, including S. mutans, to facilitate the insertion of certain cell surface proteins, containing an LPXTGX motif such as antigen I/II. This study examined the effect of nicotine on the function of sortase A to control the physiology and growth of S. mutans using wild-type S. mutans NG8, and its isogenic sortase-defective and-complemented strains. Briefly, the strains were treated with increasing amounts of nicotine in planktonic growth, biofilm metabolism, and sucrose-induced and saliva-induced antigen I/II-dependent biofilm formation assays. The strains exhibited no significant differences with different concentrations of nicotine in planktonic growth assays. However, they had significantly increased (Pf0.05) biofilm metabolic activity (2-to 3-fold increase) as the concentration of nicotine increased. Furthermore, the sortase-defective strain was more sensitive metabolically to nicotine than the wild-type or sortase-complemented strains. All strains had significantly increased sucrose-induced biofilm formation (2-to 3-fold increase) as a result of increasing concentrations of nicotine. However, the sortase-defective strain was not able to make as much sucrose-and saliva-induced biofilm as the wild-type NG8 did with increasing nicotine concentrations. These results indicated that nicotine increased metabolic activity and sucrose-induced biofilm formation. The saliva-induced biofilm formation assay and qPCR data suggested that antigen I/II was upregulated with nicotine but biofilm was not able to be formed as much as wild-type NG8 without functional sortase A.