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Astragalus (AS), a traditional Chinese tonic medicine, refers to the dry root of perenial herbaceous plants Astragalus membranaceus (Fisch) and Astragalus mongolicus Bge of leguminosae family, which was first recorded in "Shen Nong's Herbal Classic" (神农本草经). The herb is sweet in flavor, slightly warm in nature and acts on the Spleen and Lung channels. It was described that AS possesses the effects of "invigorating Qi to elevate Yang，consolidating superficies to stop sweating, inducing diuresis to remove edema and promoting healing of sore to regenerate tissue". Its chemical components have been discovered to be AS-saponins (ASS), AS-general flavone (AGF), AS-polysaccharides (APS), amino acid and microelements. During the past two decades, the effects of AS, the prescriptions containing AS and its active components on cardiovascular system have been widely studied(1,2). Its effects of positive inotropic action，reducing blood pressure, and in protecting myocardia against injuries caused by ischemia and ischemia/reperfusion or virus infection have been well documented. The underlying mechanisms of the effects have also been deeply studied. This paper summarizes the pharmacological studies on the effects of AS on cardiovascular system conducted in recent years.
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藏药鬼箭锦鸡儿化学成分及药理作用的研究进展
藏药鬼箭锦鸡儿[Caragana jubata(Pall.)Poir.],又名冠毛锦鸡儿,别名鬼见愁或浪麻,藏名"着母香、啄木兴",系豆科蝶形花亚科锦鸡儿属植物,具有很高的营养、药用和观赏价值,也是抗干旱耐瘠薄的造林先锋树种.分布于我国青海、西藏、新疆、甘肃、宁夏、内蒙古等省区的高山和亚高山地区,辽宁、河北、山西、陕西、四川等地的山区也有分布,多生长在海拔3000 m以上的砾石山坡、沟缘及林下.藏医民间用药常以藏药鬼箭锦鸡儿根部带红色的木质部芯材为主,其具有活血化瘀、凉血降压、生肌止痛的功能,可用于防治多血症、血热症、高血压病和心血管等方面的疾病 [1-2].本文对其化学成分及药理作用作一概述.
