首页 > 文献资料
-
To approach the mechanism of lipopolysaccharide (LPS) in causing acute lung injury (ALI) and the protective effect of rhubarb and dexamethasone, lung specimens were examined with macroscopy, microscopy, electron microscopy and the biological markers of ALI including lung wet/dry weight, the rate of neutrophils and protein content in the pulmonary alveolar lavage fluid, pulmonary capillary permeability and pulmonary alveolar permeability index were observed. The mechanism of the ALI is mainly due to direct injury of alveolar epithelium and pulmonary vascular endothelium. Rhubarb and dexamethasone could significantly reduce the edema of the lung tissue, decrease the red blood cell exudation, neutrophil infiltration and plasma protein exudation in the alveoli and all the biological markers in comparison with the ALI model rats, indicating they have protective action on vascular endothelium and alveolar epithelium.
-
火把花根片改善类风湿性关节炎关节疼痛、晨僵效果体会
Background: Rheumatoid arthritis is a kind of chronic systemic autoimmune diseases that invade mainly in articulation. In the early time, it shows wandering pain and dysfunction, and in the late time, it shows stiffness、 deformation of articulation and lose of function. There is no special and nonpoisonous side－ effect effective drug now. Huobahuagen is a kind of special Chinese drug in Southwest, its main ingredients are biological base、 terpines、 lactone、 phenol acid etc. could inhibit inflammatory capillary permeability, decrease exudation and inhibit proliferation.
