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Acute lung injury ( ALI) is induced by direct and indirect injury,and It causes the damage of alveolar epithelial cells and capillary endothelial cells. Acute lung injury is characterized by Acute lung injury is characterized by the development of hypoxemia,damage to the alveolar capillary membrane barrier,pulmonary ede-ma, and the resultant respiratory failure Acute lung injury ( ALI) and acute respiratory distress syndrome ( ARDS) in their most severe forms are still major challenges in modern intensive care medicine that significantly contribute to morbidity and mortality of critically ill patients. there is no particularly effective treatment , so far. it is still a Thorny Medical Problem all of the world. Bone marrow mesenchymal stem cells ( BMMSC) is the another type of stem cell other than the bone marrow hematopoietic stem cells . BMMSC is understudied deeply with the indepth study of cell biology. It provides a new way for the treatment of ALI as the characteristics that can survive damage lung tissue in mice and differentiated into alveolar epithelial cells, repair damaged lung tissue. This paper reviews the potential therapeutic effect of BMMSC to ALI and its mechanism.
