Objective:To analysis through the mouth atlanto-axial vertebral anterior plate fixation in finite element for the development of the segmental anterior fixation surgery and to provide the reference of inner plant im-provement. Methods:One case, male, 36 years old, 64 kg weight was randomly selected from January 2014 to our hospital to check no-skull - atlanto-axial vertebral disease . It was scanned by 0. 625 mm thin layer, Image data were rebuilted in the Mimics 16. 01 software, Pro/ENGINEER 4. 0 software was used to rebuilt atlanto-axial vertebral anterior plate, After reconstruction of steel screw 3 d model according to the classic through the mouth , the model was imported into Mimics 16. 01 and the model surface was meshed and material was assigned, The mod-el was forced 80 N vertical loading, the surface was applied 15 nm torque, to simulat three motion state example, forward bends, stretch, side-bending, The stress and deformation of screw and rod were measured. Results: At-lanto-axial vertebral three-dimensional reconstruction model were divided into 14 514 individual grid, 7 257 nodes, the model was loaded, The stress of upper screw root in bend was biggest (62. 34 ±5. 52) Mpa (F=73. 23, P<0. 05, the difference was statistically significant). A screw of the root and the top, lateral stress was the largest, respectively were (78. 42 ± 5. 5. 14) Mpa (F=112. 32, P<0. 05);(95. 48 ± 7. 12 Mpa (F=62. 32, P<0. 05), the difference was statistical significance; Under three different motion state and a screw root stress, Upper screw root stress in bending forward was greater than the lower (forward bends, stretch and lateral bending state , t value were 12. 2, 9. 23, 22. 98, P<0. 05, differences were statistically significant), and in the lateral current screw root stress was greater than the upper; In the same movement state, the top was greater than the root, the differences were statistically significant (forward bends, stretch and lateral bending state after t value were 23. 14, 22. 01, 8. 13, P<0. 05). Conclusions: Through the mouth atlanto-axial vertebra fixed system stress distribution wad more reasonable, could withstand normal atlanto-axial after vertebral motion bearing stress, but the postoperative patients should reduce the proneness and lateral movement, and to the risk of fatigue fracture fixation system.