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AIM To explore a method to control splenic embolic volume precisely for partial splenic embolization(PSE) to improve the validity and safety of PSE, and study the portal hemodynamic changes after PSE.METHODS Gelfoam particles of identical standard (2×2×1.6mm) were used as embolic material tomeasure the splenic radiographic parameters SAI (spleen activity index) was measured scanning withradioisotope technetium-99mTc sulfur colloid and splenic embolic volume was calculated with the followingformula: splenic embolic volume = [SAI(pre-PSE)-SAI(post- PSE )]/SAI(pre-PSE)×100%. The regressionequation of gelfoam particles in splenic embolic volume and splenic radiographic parameters was calculatedusing SAS (statistical analysis system) software (version 6.02). Portal hemodynamic changes were examinedby color Doppler ultrasound.RESULTS The amount of gelfoam particles was correlated with splenic embolic volume and top-bottomlength of spleen, regression equation was achieved: Y = 5.77X1 + 15.19X3-164.75, (multi-regression wasused, significant level P = 0.15). Y: number of gelfoam particles used, Xl: splenic embolic volume (%),X3: top-bottom length of spleen (cm). The diameter and blood flow volume of spleen and portal vein and thepeak velocity of spleen vein all decreased after PSE. The decreased parameters were positively correlatedwith splenic embolic volume.CONCLUSION By calculating gelfoam particles for PSE, splenic embolic volume could be controlled withinthe effective and safe limit. PSE could decrease the high dynamic circulating state of portal systemeffectively.
