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“采用双末端大规模平行测序对孕妇尿液中的胎儿DNA的高分辨率分析”点评
1论文题目及原文摘要1.1 论文题目High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-End Massively Parallel Sequencing1.2 摘要Background Fetal DNA in maternal urine,if present,would be a valuable source of fetal genetic material for noninvasive prenatal diagnosis.However,the existence of fetal DNA in maternal urine has remained controversial.The issue is due to the lack of appropriate technology to robustly detect the potentially highly degraded fetal DNA in maternal urine.