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Three-dimensional reconstruction nerve models are classically obtained from two-dimensional ages of “visible human” frozen sections. However, because of the flexibility of nerve tissues and smal color differences compared with surrounding tissues, the integrity and validity of nerve tissues can be impaired during mil ing. Thus, in the present study, we obtained two-dimensional data from a healthy volunteer based on continuous CT angiography and magnetic resonance myelography. Semi-automatic segmentation and reconstruction were then conducted at different thresholds in different tissues using Mimics software. Smal anatomical structures such as muscles and cervical nerves were reconstructed using the medical computer aided design module. Three-dimensional digital models of the cervical nerves and their surrounding structures were successful y developed, which al owed visualization of the spatial relation of anatomical structures with a strong three-dimensional effect, distinct appearance, clear distribution, and good continuity, precision, and integrality. These results indicate the validity of a three-dimensional digital visualization model of healthy human cervical nerves, which overcomes the disadvantages of mil ing, avoids data loss, and exhibits a realistic appearance and three-dimensional image.
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刺激迷走神经后不同组织肿瘤坏死因子变化的实验研究
AIM:To investigate the effect of proinflammatory cytokine and anti inflammatation cytokine on liver and lung tissues in rats with endotoxemia.METHODS:Male Wistar rats were randomly divided into 4 groups: group treated with stimulating vagus nerve, group receiving lipopolysaccharide(LPS) intravenous injection after transecting vagus nerve, group treated with sham operation and group treated with injecting LPS intravenously alone, and then measured the levels of TNF α in liver and lung and those of cortisol and Alanine aminotransferase (ALT) in plasma.RESULTS:Compared with group treated with sham operation,LPS treated groups showed a significant increase in TNF level, which was at most 15 fold higher than that of the former group.There was a significant decrease in TNF level in group treated with stimulating vagus nerve,compared with both group receiving LPS intravenous injection after transecting vagous nerve and group treated only with LPS.In addition,we observed plasma cortisol level in LPS treated group was much higher than other 3 groups and the plasma ALT level was greatly lower than that of group treated only with LPS.CONCLUSION:Stimulating vagous nerve can significantly decrease the production of proinflammatory cytokine and alleviate inflammation in rats with endotoxemia.
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小儿颈部囊状水瘤
我院外科自1975年~1980年共收治小儿颈部囊状水瘤38例,分析和讨论如下:临床资料一、一般资料:男性29例;女性9例.年龄小为5天,大为9岁.1岁以下16例,1~3岁9例,3岁以上13例.