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Estimation of the state of the hemostasis system in patients with tubercular infection by the method of low-frequency vibration piezoelectric hemocoagulography
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Thrombin Activable Fibrinolysis Inhibitor
The zymogen thrombin activable fibrinolysis inhibi-tor (TAFI), also known as procarboxypeptidase U (proCPU), was first described by Hendriks and cowork-ers in 1989.
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The fate of a forming thrombus is determined through the delicate balance between the coagulation cascade (favouring clot formation) and the fibrinolytic system (favouring clot lysis). These processes occur simultaneously, and enhancement of endogenous fibrinolysis has been shown to reduce occlusive thrombus formation in animal models.