关节腔内注射玻璃酸钠治疗肩周炎的疗效分析

肩关节周围炎(肩周炎)是骨科门诊的常见病、多发病,多因风寒侵袭、外伤或过度疲劳所致,使肌腱、韧带、滑囊、关节囊等软组织发生充血、渗出、水肿、粘连的无菌性炎症,表现为肩部疼痛,肩关节活动受限.特点:夜间疼痛加剧,甚至夜不能眠.电脑工作者肩关节的活动相应减少,长期缺乏运动,使肩周炎的发病率有明显上升趋势.我院临床开展了玻璃酸钠注射治疗肩周炎,取得一定疗效.现报告如下.

玻璃酸钠关节内注射治疗膝关节骨性关节炎的临床研究

骨性关节炎(osteoarthritis,OA)又称退行性关节病、骨质增生、骨关节病,是以关节软骨进行性损害为特征的慢性关节紊乱综合征,是中老年常见疾病,其病理变化包括软骨退变,软骨下骨硬化及囊性变形使关节边缘骨质增生以及滑膜慢性炎症等.

玻璃酸钠治疗骨性关节炎的临床疗效观察

骨性关节炎(OA)是中老年常见的一种慢性病.它是由多种因素造成的,除了机械磨损外,还有免疫、生化和遗传等因素.病理改变以软骨变性及软骨下骨质病变为主,还有滑膜的改变.临床表现为关节疼痛、肿胀和功能障碍.其治疗方法较多,早期一般采用非手术疗法,晚期多主张手术疗法.

玻璃酸钠注射液治疗肩关节周围炎的临床观察

肩关节周围炎是骨科门诊的常见病、多发病.好发于中年女性,为自限性疾病,大部分在10个月内恢复,但容易复发.目前治疗肩关节周围炎的方法有多种,如封闭、按摩、理疗、熏洗等,通过精心的护理可取得一定的疗效.其中局部封闭方法多采用激素药物配以局部麻醉药,多次使用容易腐蚀肩周肌肉及肌腱,引起关节骨疏松,使其功能退化.就此我院临床开展了玻璃酸钠注射液治疗肩关节周围炎,取得一定疗效,现将其介绍如下.

施沛特关节腔内注射加穴位注射缓解膝关节炎疼痛的疗效分析

Background:Osteoarthritis belongs to regressive diseases.A lot of inflammatory cells were observed in inflammatory tissues.Shipeite was the sodium hyaluronate extracted from cockscomn which is the main elements of artucykar cartilage and synovial fluid. Objective:To reduce pain caused by gonarthritis through shipeite injection of articular cavity and acupoint. Design:According to diagnosis criteria for osteoarthritis of American Rheumatology Association,181 patients with gonarthritis were included in our study. Unit:People's Hospital of Jiangxi.

BACKGROUND: Studies have shown that sodium hyaluronate inhibits cartilage damage in osteoarthritis and accelerates regeneration of cartilage cels, to stabilize and repair the articular cartilage.
OBJECTIVE:To investigate the therapeutic effect of sodium-rich plasma combined with platelet-rich plasma (PRP) on rabbit knee osteoarthritis.
METHODS:Forty New Zealand white rabbits were randomly divided into five groups, control group, combined group, sodium hyaluronate group, PRP group and model group, and then an osteoarthritis model of the right knee was made in each rabbit. After modeling, sodium hyaluronate+PRP, sodium hyaluronate, autologous PRP and normal saline were givenviathe knee joint cavity in the latter four groups, respectively, once a week for 5 weeks. The control group received no treatment, as normal controls. At 1 week after treatment, ELISA assay was used to detect serum interleukin-1, interleukin-6, tumor necrosis factor-α levels, and changes of the articular cartilage were observed under a light microscope.
RESULTS AND CONCLUSION:Compared with the control group, the levels of interleukin-1, interleukin-6 and tumor necrosis factor-α were al increased in the other four groups (P < 0.01). Compared with the model group, the levels of interleukin-1, interleukin-6 and tumor necrosis factor-α were lowered significantly in the combined, sodium hyaluronate and PRP groups (P< 0.01 orP< 0.05), and the most significant decline was in the combined group. Articular cartilage damage was severest in the model group and mildest in the combined group. Experimental findings indicate that intra-articular injection of sodium hyaluronate+PRP can reduce inflammation and protect the articular cartilage in knee osteoarthritis, which is better than a single drug injection.

不同分子量玻璃酸钠治疗指屈肌腱狭窄性腱鞘炎的疗效和成本-效果分析

指屈肌腱狭窄性腱鞘炎是骨科和手外科门诊中较常见的疾病.患病人群已由传统手工业者向现代电脑族、手机族转变,且有发病年青化、多指化的趋势.应用玻璃酸钠(sodium hyaluronate,SH)治疗指屈肌腱狭窄性腱鞘炎临床疗效肯定[1].但是对不同分子量SH的作用,以及如何选择价格适宜的产品,我们运用药物经济学成本-效果分析法[2],对2个厂家、不同分子量、不同价格的SH进行比较,以期在提高临床疗效的同时,降低医疗成本.