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Searching for Susceptibility Genes in Age-related Macular Degeneration:An Evolutionary Process
Age-related macular degeneration(AMD) is a complex disease with multiple risk factors. Although the pathogenesis and etiology remain largely unclear, systematic investigation into the genetics of this disease has cumulated during the past two decades that leads to putative mechanisms and genes associated with AMD. In this review, the development of genetic studies on AMD was summarized. While we intend to perform a comprehensive citation of all published works on AMD genetics, we find that we have to filter out some reference papers and focus on those reports bearing more information and insight into AMD genetics and its molecular pathology. We have worked on a selection of observations and supporting references that illustrate a picture of the genetic processes that eventually lead to the development of AMD and related complications.
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某染料厂22例联苯胺致膀胱癌分析
在我国泌尿系统肿瘤中,膀胱癌的发病率和死亡率均占首位[1].流行病学调查资料表明,25%~27%的膀胱癌患者可能因接触芳香族化合物(如联苯胺)引发.天津市染料行业曾有8个厂的千余名工人从事联苯胺染料的生产和联苯胺硫酸盐的制造工作,某染料厂自1970年发现首例膀胱癌患者至今,40年来已确诊职业性膀胱癌22例,现将其疾病的发生、发展及转归情况进行总结分析.
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走出药房,参与临床
近日,新医改方案公布,其中有不少让临床药师欢欣鼓舞的内容,不管是为群众提供更好的医疗卫生服务的总目标,还是与之配套的公立医院改革、健康教育宣传、基本药物制度、药物的合理使用和患者的安全用药、建立医药信息系统等,药师群体都是保障其实施的主力军,而这一系列举措中涉及的措施就有完善医疗机构用药管理、处方审核制度,发挥医疗机构和药学技术人员在规范临床用药中的作用,建立基本药物使用和合理用药监测考核评估制度等.