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Objective: To evaluate the effect of Chinese herbal medicine (CHM) in the process of corticosterone (CS) reduction in nephrotic syndrome. Methods: One hundred and twenty patients of idiopathic nephrotic syndrome sensitive to prednisone treatment were divided into two groups randomly. The dosage of prednisone used was conventionally reduced in both groups but CHM herbal treatment was added to the treated group in the period of prednisone reduction. The effect of CHM was estimated by observing the recurrence rate of disease and side-effects of prednisone. Results: The recurrence rate of disease and the occurrence rate of side-effects of prednisone in the treated group were less than those in the control group significantly (P<0.01). Conclusion: Additional CHM in the process of CS reduction in treating CS sensitive nephrotic syndrome could markedly abate the recurrence rate of disease and the side-effect of CS reduction.
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全直肠系膜切除术治疗直肠癌
结肠和直肠癌是第三位常见癌.直肠癌约占其三分之一.其中50%~60%的患者能切除.通常在这些患者中约20%~30%在切除部位复发.局部复发率(local recurrence rate,LRR)取决于肿瘤的分期,在Dukes C期肿瘤中LRR超过40%的并不少见.在50%~80%的患者中局部复发是缘于局部手术治疗的失败[1].如何减少LRR,提高生存率,是目前治疗直肠癌所面临的主要问题.文献报告全直肠系膜切除术(total mesorectal excision,TME)可使LRR 降低到10%以下,本文就有关问题综述如下.
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综合康复治疗对偏头痛患者的作用
BACKGROUND:Migraine is a common disease in department of neurology,but it is often overlooked because doctors think patients will recover after some time even without treatment.Although patients feel headache,they don't get to the degree looking for treatment.So therapeutic effects appeared slowly with high recurrence rate.
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心理行为干预对颈性眩晕患者康复效果的影响
BACKGROUND:Cervical vertigo(CV) belongs to vertebral artery type of cervical spondylopathy which clinical manifestation was paroxysmal vertigo and is highly related to cervical motion.Recent clinical experiences proved that comprehensive treatment was superior to simple treatment.Because of patients were in different departments,therapeutic methods were also different,effects produce slowly,remote effects were not obvious and recurrence rate was higher.
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对老年缺血性脑血管疾病脑血流及功能分析
BACKGROUND: The ischemic cerebrovascular disease ofsenile patients has the features of high recurrence rate, bad prognosisand many influence factors. The coming out of CT makes diagnosis ofcerebrovascular disease getting reliable foundation. But the diagnosisof CT can not determine the location of specific blood vessels ofresion, especially the ischemic changes caused by spasm and nar-rowness of blood vessels in early period. In addition, examination ofcerebral angiography can cause trauma, so patients with severecerebrovascular disease can not endure it.
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小儿颈部淋巴管瘤的手术治疗
作者报告小儿颈淋巴管瘤手术治疗69例,其中全切除48例,大部分切除21例.46例获随访观察,远期疗效优良者41例,疗效差者5例.本病虽为良性,但易合并出血和感染,应早期手术.对粘附于重要血管、神经等不能完全切除的肿瘤,行大部分切除,残留囊壁涂以碘酒,可获长期治愈,复发率仅为10.9%.
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腹腔镜治疗>5 cm胃GIST是否安全可行:前瞻性队列研究结果
目的:由于担心术中肿瘤破裂,腹腔镜手术治疗>5 cm胃GIST仍存争议。方法:为探讨腹腔镜手术切除>5 cm胃GIST的可行性及安全性,我们于2011年3月至2015年3月入组一前瞻性研究队列。研究主要终点为术中肿瘤破裂发生率;次要终点包括:中转开腹率、手术时间、手术出血量、恢复流食及固体食物时间、术后住院时间及随访期间肿瘤复发率。结果:共有22例患者进入研究队列,平均肿瘤直径(7.04±1.53)cm,范围:(5.2~10.8cm),无术中肿瘤破裂。平均手术时间(88.1±31.9)min,估计手术出血量(37.1±18.7)mL,无需输血病例。恢复流食及固体食物时间分别为(1.1±0.6)d及(2.5±0.9)d。平均术后住院时间为(5.4±5.8)d。平均随访时间为(18.9±10.2)月,范围:(2~47月),随访期内无复发病例。结论:腹腔镜手术切除>5 cm胃GIST安全、可行。
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Whole breast radiotherapy afier tumor lumpectomy is based on the premise that that the breast cancer recurrence rate is reduced through the elimination of residual cancer foci in the remaining tissue immediately adjacent to the lumpectomy site and occult multicentric areas of in situ or infiltrating cancer in remote areas of the breast. The relevance of remote foci to ipsilateral breast failure rates after breast conserving treatment is debatable, because 65%~100% of recurrences develop in the same quadrant as the initial tumor. This has led several investigators to question whether radiotherapy must be administered to the entire breast.
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减张疝修补术的临床总结
传统疝修补术局部张力高,复发率高。无张力修补复发率低但费用高,且有异物有排异风险同时增加感染风险。笔者对传统修补稍作修改,姑称减张修补术,既不增加费用,又有无张力修补术复发率低的优点。