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功能性食物在美国
2002年6月8~18日应美国食品工业学家学会(IFT)专业发展部主任Dean D.Duxbury先生及美国Draco Natural Products Co.总裁Jerry Wu先生的邀请,我们在美国加利福尼亚州Anaherim会议中心参加了IFT2002年年会及食品博览会(Food Expo).来自世界各地的1500余家食品工业公司参加了展示.为期两天的专题报告共2000篇左右,涉及内容非常广泛,包括10个专题:(1)基础科学;(2)粉状食物的技术与应用;(3)水的功能及其基础;(4)食品安全性的设计;(5)技术专业的管理计划;(6)食品添加剂技术;(7)食品加工业的管理与质控;(8)正确测定消费者对食品的接受程度和市场调研;(9)成功销售与谈判技巧;(10)制定有效的食品配制和开发程序.我们参加"食物添加剂技术组",该组有15位专家作了报告,主讲植物学的只有我们一家,其余都属西方营养学的内容,诸如:抗菌系统,食物色素,抗氧化问题;功能性类脂质,高功能甜味剂,辣味浸出液,水化胶体,添加剂风味及脂肪替代品等.
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Jadomycin B, an Aurora-B kinase inhibitor discovered through virtual screening
Aurora kinases are clearly implicated in tumorgenesis and have emerged as promising targets for cancer therapy in recent years. In a virtual screening attempt, 22 compounds were identified from nearly 15,000 microbial natural products as potential small-molecule inhibitors of human Aurora-B kinase. When tested in yeast models, 2 compounds (one is Jadomycin B) showed preferential inhibition of ipll-321 (yeast Aurora kinase temperature sensitive mutant) than wild type yeast cell, suggesting these compounds are true Aurora kinase inhibitors. Further in vitro biochemical assay using purified recombinant Aurora-B kinase showed Jadomycin B inhibits Aurora-B activity in a dose-dependent fashion while two Jadomycin congeners, Jadomycin S and T, showed no activity.
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Journal of Natural Products简介
Journal of Natural Products(<自然产品杂志>;ISSN:0163-3864;e ISSN:1520-6025)是由美国化学会(American Chemical Society)和美国生药学会(American Society of Pharmacognosy)联合出版的一本药物化学及生药学类杂志.杂志于1979年创刊于美国芝加哥,每月出版一期.现任主编为芝加哥伊利诺州大学的A.Douglas Kinghorn.该杂志现已被CAS,Scopus,EBSCOhost,British Library,PubMed,Ovid,Web of Science及SwetsWise等多家数据库收录.Journal of Natural Products 2007年的ISI影响因子为2.551.
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Journal of Asian Natural Products Research简介
Journal of Asian Natural Products Research(<亚洲天然产物研究杂志>,简称JANPR;ISSN:1028-6020;e-ISSN:1477-2213)是由英国Taylor & Francis公司出版发行的一本以亚洲传统医学中天然产品的化学和药理学研究为主要方向的国际性杂志.
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国际海洋天然产物研究进展及展望--第10次国际海洋天然产物研讨会简介
国际海洋天然产物研讨会(InternationalSymposium on Marine Natural Products,简称MaNaPro)是反映国际海洋天然产物研究新趋势、动态和进展的重要的国际性会议,每3年举行1次.
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民族药标本资源共享平台及在生物多样性保护领域的应用展望(下)
APPLICATION PROSPECT OF SPESR IN BIODIVERSITYPROJECT1 Introduction of the International Cooperative BiodiversityGroups (ICBG) ProgramICBG program is a unique effort that addresses the interdependent issues of drug discovery, biodiversity conservation, and sustainable economic growth. The FIC-managed Biodiversity Program is designed to guide natural products drug discovery in such a way that local communities and other source country organizations can derive direct benefits from their diverse biological resources.Benefit-sharing may provide clear incentives for preservation and sustainable use of that biodiversity.