首页 > 文献资料
-
Improvement of Cardiac Function by Dry Weight Optimization Based on Interdialysis Inferior Vena Caval Diameter(2)
Among 306 HD patients,31 fluid overloaded patients(IVCe>16mm) with a reduced EF (EF<55%) were chosen for DW optimization(WTBZTable 1).The etiology of chronic renal failure in these patients was as follows:chronic glomerulonephritis 24,diabetic nephropathy 5,lupus nephritis 1,and polycystic kidney 1. No β-blockers were used during the study period.In these patients,DW was reduced to achieve an interdialytic IVCe<16mm.
-
1例先天性多囊肾、多囊肝合并颅内动脉瘤病人的护理
常染色体显性多囊肾病是系统性疾病,病人在30岁~60岁出现临床症状,发病率(1∶400)~(1∶1 000)[1].其病理改变为肾脏皮质和髓质布满大小不等的囊肿,呈圆形或梭形.囊肿上皮细胞呈局限性增生,甚至形成息肉;囊内充满液体,外观清亮或血性;囊与囊之间可见少量正常分布的肾组织.随着年龄的增长,囊肿的数量和体积逐渐增加,进行性破坏肾脏正常的结构和功能,终导致终末期肾衰竭,可累及心血管系统、消化系统、造血系统等肾外器官.我科于2010年6月收治1例先天性多囊肾、多囊肝合并颅内动脉瘤病人,保守治疗期间进行了有针对性的护理.现报告如下.
-
多囊肾肾移植术后的临床观察及护理
我科1985年7月-2002年12月共行肾移植术642例,其中多囊肾肾移植21例,现将多囊肾肾移植术后的临床观察探讨如下.
-
新生儿多囊肾1例
患儿,男,58 h,因发现血尿,皮肤黄染34 h入院.患儿为第5胎第2产,孕39周自然分娩出生,出生体重3 200 g,出生时无窒息和产伤史,但羊水为均匀血性.于生后第2天排血性尿液,并见皮肤黄染,在当地医院就诊,住院治疗1 d后,黄疸略有消退.但血尿无好转而转来我院.父母体健,非近亲结婚,否认特殊疾病和类似疾病家族史.
-
多囊肾经皮穿刺注射复方铝溶液的疗效观察
我们采用B超引导下经皮穿刺多囊肾,囊内注射复方铝溶液(3%硫酸铝钾溶液)治疗多囊肾143例,对其安全性、有效性及远期疗效进行了随访观察,现报告如下.
-
成人常染色体显性遗传性多囊肾并发先天性肝纤维化一例
先天性肝纤维化(CHF)是常染色体隐性遗传性多囊肾(ARPKD)的常见表现,但在常染色体显性遗传性多囊肾(ADPKD)中极为罕见[1-3],经检索国内末见报道.我们报告1例成人ADPKD并发CHF和门脉高压.
-
常染色体显性遗传型多囊肾合并气肿性肾盂肾炎一例
患者,女,60岁,10年前出现反复尿频、尿急、尿痛、双下肢和面部水肿,间断服利尿剂和抗生素.入院前24 d出现洗肉水样小便和右上腹部疼痛,伴反复阵发性寒颤、高热39.8℃,每次持续4 h.
-
微卫星SM7多态信息含量的测定与应用
Ⅰ型常染色体显性遗传多囊肾病(autosomal dominant polycystic kidney diseasc Ⅰ, ADPKD Ⅰ)发病率约为1.1/1000[1],在需肾替代治疗的患者中约占10%,目前没有理想的早期诊治方法.我们应用微卫星SM7标记,对ADPKDⅠ患者进行症状前和产前诊断的可行性研究,以便早期防治,现报告如下.
-
Background: There are few studies on the genotypes and phenotypes of autosomal recessive polycystic kidney disease in Chinese patients.
Methods: PKHD1 mutations in three children were detected with PCR and direct sequencing, and their clinical data were retrospectively reviewed.
Results: All of the children had bilateral enlarged polycystic kidneys, congenital hepatic fibrosis and intrahepatic bile duct dilatation. One of three children had classical multiple small cysts throughout the kidneys, and the other two children had bilateral multiple renal cysts of various sizes. Two children had abnormally shaped livers, portal hypertension and splenomegaly. Two heterozygous mutations (p.T36M, and p.P137S) were detected in Patient 1 and two were detected in Patient 2 (p.L2658X and p.V836A). One heterozygous mutation (p.L1425R) was detected in Patient 3.
Conclusions: The study shows that renal and liver phenotypes of the Chinese children varied. Five mutations were identifi ed in the three children, three of which were novel mutations.