肺癌患者血清中p53基因突变的检测及意义

肺癌是目前严重危害人类健康的常见恶性肿瘤之一.临床上诊断为早期的一些肺癌患者外周血中可能已经有循环的肿瘤DNA[1],提示检测其外周血中的肿瘤DNA,对肺癌患者的诊断、分期和预后的判断等可能具有重要价值.

Collection of Dialysis Treatment Data and Patient-Related Information in a Single Dialysis UnitState-of-the-art dialysis machines are capable of automatically collecting huge volumes of dialysis treatment data (blood and dialysate flow rates, venous and arterial pressures, ultrafiltration rate, ultrafiltration volume, transmembrane pressure, conductivity, etc.) and displaying the information on the monitor screen. Commercially available software allows this information to be exported to a clinical database on a server through a local network in the clinic, enabling healthcare professionals to further process, display, and evaluate the data. Moreover, on-line sensors can be used to monitor patient-related information, e.g.effective ionic dialysance as a marker of urea clearance[1-3], urea removal and additional parameters(e.g. whole-body Kt/V) based on dialysate urea measurements[4,5], and blood volume changes[6]. Although many of these sensors are available in dialysis machines, their clinical value in routine dialysis is still subject to debate[7].

镍钛聚髌器治疗髌骨骨折与术后康复训练的关系

INTRODUCTIONForm remembering alloy were used broadly in clinic for its effect,special mechanics and excellent tolerance and has a clinical value[1].

开展新的降温方法,探索低温治疗的临床价值

早在20世纪初,人们就开始应用降低患者体温的方法来抢救神经科重症患者(如脑外伤),而发热是其常见的表现之一,可加重原有疾病对机体的损害.由此,也开展了大量基础研究,证实低温治疗具有脑保护作用.然而,由于技术的限制,多采用全身体表降温,如通过冰毯、酒精擦浴、腹股沟、腋窝和颈部等部位敷以冰袋、循环冷空气处理、直肠和(或)膀胱冰水冲洗等方法来降低体温;也有人采用头部重点降温,如带冰帽或半导体贴敷式降温等.这些低温诱导方法虽能达到目标温度,但其操作过程较为繁琐,诱导过程较长,而且易产生多个系统的并发症,如血小板减少、凝血功能障碍、心律失常、低血压、血栓形成、肺炎和败血症等.

血清中CEA、SF、HA检测对肺癌的诊断价值

近几年来,支气管肺癌(下称肺癌)的发病率和病死亡率不断增高[1].肺癌是高转移、高复发的肿瘤之一.因肺癌早期症状的不典型及多样性,导致早期肺癌发现率较低,误诊漏诊率仍很多,所以提高肺癌的诊断水平是肿瘤临床工作的当务之急;也是提高肺癌患者生存率,降低病死率的关键.肿瘤标志物的研究是现代肿瘤学研究的重要课题,单一标志物的测定对肺癌的诊断有一定的局限性.

80例小儿肾肿瘤误诊原因分析

我院自1963年1月～1980年12月收治14岁以下小儿肾肿瘤80例,其中76例经手术或病理证实,4例未手术者根据临床表现及静脉肾盂造影诊断.

95例输卵管妊娠的阴道超声图像分析及临床意义

孕卵在宫腔以外地方着床称为异位妊娠,习称宫外孕.因孕卵种植位置不同,可分为输卵管妊娠、卵巢妊娠、腹腔妊娠、宫颈妊娠、间质部妊娠、残角妊娠等.其中以输卵管妊娠为多见,约占异位妊娠的95%以上[1].输卵管妊娠的早期诊断,是指孕卵在输卵管未破裂前或早期流产破损所作出的诊断.本文通过对95例输卵管妊娠的阴道超声图像进行分析,以探讨阴道超声对输卵管妊娠早期诊断及治疗的临床意义 .

肥胖儿童颈动脉内中膜厚度、弹性指标及内皮功能测定的临床价值

根据国际肥胖工作组的筛查发现，目前在发达国家中2～18岁儿童中肥胖检出率约为6％～8％［1］。国内研究［2］同样表明中国儿童肥胖率近年呈明显增加趋势，且在不同性别、年龄和地区增长趋势相似。儿童时期的肥胖与成人期心血管疾病及大范围的健康问题发病风险密切相关。本组应用颈动脉超声的检测对单纯肥胖儿童血管功能作出评价，为肥胖儿童的防控提供可靠的量化指标。

Chemotherapy, endocrine therapy and molecular targeted therapy are vital means in the treatment of metastatic breast cancer (MBC), whose reasonable and standard applications are of great importance to prolong patients’ survival and improve the quality of life. The expressions of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor-2 (HER-2) present signiifcant differences between primary and metastatic breast cancer. However, these differences may affect the selection of MBC patients for therapeutic strategies and judgment on the prognosis. Hence, the relevant researches on variations of hormone receptors and HER-2 in primary and metastatic breast cancer, discordant causes of ER, PR and HER-2 expression in primary and metastatic lesions and clinical value of biopsy to the metastases are reviewed in the study.